My friend Kelly asked me for some advice about blister prevention, so I wrote up my answer as a running tip, in case there were others who were interested. Having non-HS RDEB, I have rather more experience with blisters than I would like. However, if I can avoid blisters, you should be able to!
http://fellrnr.info/Blister-Prevention
Yes I think socks matter a lot too. I have not had any blister problems whatsoever since I started wearing DryMax socks.
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